LaserCap™ Clinical Studies in women and men with thinning hair:

Hair Re-growth: Clinical Study of LaserCap™ as a hair re-growth device in women and men with thinning hair.  This study aims to demonstrate  LaserCap’s ability to cause dormant Telogen Phase hair follicles to cycle to Anagen Phase growth. 

Hair Shaft Thickening: Clinical Study of LaserCap™ as a hair thickening device in women and men with thinning hair.  This study aims to demonstrate  LaserCap’s ability to improve the Anagen Phase growth of hair follicles, resulting in increased hair shaft thickness and/or a reduction in hair shaft thinning.  Hair pigment will also be assessed.

Hair Growth Rate Increase:  Clinical Study of LaserCap™ as a device to increase hair growth rate. This study aims to demonstrate  LaserCap’s ability to improve the Anagen Phase growth of hair follicles, resulting in an increased rate of hair growth.

Hair Length Increase:  Clinical Study of LaserCap™ as a device to grow hair longer. This study aims to demonstrate  LaserCap’s ability to prolong the Anagen Phase growth of hair follicles, resulting in longer hair.

Combination Treatment Studies:  Each of the above with combination LaserCap™ and topical pharma hair re-growth agent(s) (i.e., Liquid & Light Rx).

LaserCap™ Clinical Studies in women and men undergoing hair transplant procedures:

Increased Hair Transplant Follicle Survival:  Clinical Study of LaserCap™ as a device to increase the survival of  transplanted hair follicles.  This study aims to demonstrate  LaserCap’s ability to increase the survival of transplanted hair follicles by pre-transplant treatment of the donor site with LaserCap™.

Reduced Donor Hair Shedding after Hair Transplant:  Clinical Study of LaserCap™ as a device to reduce post-transplant donor hair shedding.  This study aims to demonstrate  LaserCap’s ability to reduce the number of donor hairs that shed after hair transplant by post-transplant treatment of the recipient site with LaserCap™.

Increased Hair Transplant Follicle Survival and Reduced Donor Hair Shedding after Hair Transplant:  Clinical Study of the combination of pre- and post-transplant treatment with LaserCap™.

Study Notes: Low Level Laser Treatment has been shown to be safe (Appendix A).  Low Level Laser Treatment has been shown to be effective (Appendix B).  LaserCap™ has been shown to be a non-significant-risk low level laser treatment device (Appendix C).  All eligible study subjects must complete the pre-study questionnaire (Appendix D).  All eligible study subjects must sign the consent form (Appendix E).  Study subjects will receive either a full-head illumination LaserCap or a half-head illumination LaserCap™ for as much as daily home use of 30-60 minutes, and will keep a written log of usage and comments.  Subjects will be instructed to not use any other hair re-growth treatments during the study period.  Subjects will agree to mail in to the study’s Hair Analysis Lab, tiny samples of around 25-50 clipped hairs at around 0, 60, 120, and 180 days of the study; these tiny hair samples will be clipped from front and crown treatment areas and low-occiput or side control area, and thus, all subjects will serve as their own control. (Appendix F) [Those on half-head illumination LaserCaps could be switched to full-head illumination as early at 60 days, if Hair Analysis Lab results show a significant difference between treatment and control side.  In addition, (blinded) subjects with full-head/low-intensity (10% of the treatment dosimetry) LaserCaps will serve as an additional control group]

Study Costs:  Each LaserCap™ study cost is substantial and is estimated at around $__________/subject on average, including LaserCap™ use.  There is some funding to cover some costs; however, subjects using full-illumination LaserCaps over the 6 month study periods may be asked to bear up to $_________ over 6 months to cover a portion of these study costs. 

About the Company and LaserCap™: Transdermal Cap, Inc. was formed in 2006 by co-inventors Michael Rabin, MD and M.I.T.-trained optical physicist David Smith, PhD, in collaboration with Harvard-based photomedicine expert Michael Hamblin, PhD and internationally acclaimed hair restoration physician Robert Haber, MD, to develop innovative light-based devices for the Global Beauty & Health Industries.  Its first commercial product is LaserCap™ for women and men with thinning hair or at risk for thinning hair, a condition that affects up to 50% of adult women and 80% of adult men.  LaserCap™ represents a quantum leap in low level laser treatment for thinning hair as it provides a portable (battery powered)  and wearable-under-any-hat, home-use device that delivers >2x the low-level light power of  $50,000 retail physician-office laser dome devices;  this dosimetry level is thought to be essential for maximum effectiveness.  Furthermore, the in-office laser dome treatments may cost patients up to $5,000 over 52 weeks and require them to visit the physician office at least 2x/week over the 52 week period, whereas LaserCap™ will be priced considerably less, and its portability & home-use convenience make compliance a non-issue.   

Patents Pending / Copyright 2009 / Transdermal Cap, Inc. / 55 Public Square, #1510 / Cleveland OH   44143 / 1-440-241-1846 begin_of_the_skype_highlighting              1-440-241-1846      end_of_the_skype_highlighting / info@hairlasercap.com 1/10